Description

Ethyl 5-(Aminocarbothioyl)-6-Methyl-2-(Trifluoromethyl)Nicotinate is a high-value, multi-functional heterocyclic building block characterized by its nicotinate core, trifluoromethyl group, and thiourea moiety. This compound matters for its role as a critical synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and thiourea structures.
• Chemical Research & Development: Serves as a versatile scaffold for creating libraries of compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers or ligands for catalytic systems, utilizing its metal-coordinating thiocarbonyl group.

Basic Information

Product Name	Ethyl 5-(Aminocarbothioyl)-6-Methyl-2-(Trifluoromethyl)Nicotinate
CAS No.	651292-55-6
Molecular Formula	C11H10F3N3O2S
Molecular Weight	305.28 g/mol
Synonyms	Ethyl 5-(aminothioxomethyl)-6-methyl-2-(trifluoromethyl)nicotinate; 2-(Trifluoromethyl)-6-methyl-5-thioureidonicotinic acid ethyl ester; 5-Carbamothioyl-6-methyl-2-(trifluoromethyl)nicotinic acid ethyl ester; Ethyl 5-carbamothioyl-6-methyl-2-(trifluoromethyl)nicotinate; 651292-55-6; Nicotinic acid, 5-(aminothioxomethyl)-6-methyl-2-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-(Aminocarbothioyl)-6-Methyl-2-(Trifluoromethyl)Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.