Description

Spiro[1,3-Dioxolane-4,3-[7]Oxabicyclo[4.1.0]Heptane]-2,2-Dione, 5-Hydroxy-, (1R,5S,6R)- (9Ci) is a complex, stereochemically defined spirocyclic compound with significant potential as a key chiral intermediate in advanced organic synthesis. Its intricate fused-ring structure, incorporating dioxolane and oxabicycloheptane motifs, makes it a valuable scaffold for constructing molecules with precise three-dimensional architecture. This compound is primarily sought by pharmaceutical and fine chemical research organizations for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system or requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a starting material or reagent in catalytic asymmetric reactions to induce high enantiomeric excess in target molecules.
• Ligand and Catalyst Development: Its rigid, oxygen-rich structure makes it a candidate for developing novel chiral ligands or organocatalysts.
• Material Science Research: Investigated as a monomer or precursor for creating polymers with unique thermal or mechanical properties derived from its spirocyclic core.
• Agrochemical Synthesis: Potential intermediate in the development of new, stereospecific herbicides or plant growth regulators.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Product Name	Spiro[1,3-Dioxolane-4,3-[7]Oxabicyclo[4.1.0]Heptane]-2,2-Dione, 5-Hydroxy-, (1R,5S,6R)- (9Ci)
CAS No.	649572-58-7
Molecular Formula	C8H8O5
Molecular Weight	184.15 g/mol
Synonyms	(1R,5S,6R)-5-Hydroxyspiro[1,3-dioxolane-4,3'-[7]oxabicyclo[4.1.0]heptane]-2,2'-dione; 5-Hydroxyspiro[1,3-dioxolane-4,3'-[7]oxabicyclo[4.1.0]heptane]-2,2'-dione, (1R,5S,6R)-; Spirocyclic hydroxy dioxolane-oxabicycloheptanedione; (1R,5S,6R)-isomer of CAS 649572-58-7; Chiral spiro-dioxolane derivative; Oxaspiro compound 649572-58-7
EINECS	Contact for details

Quality Control

Every batch of our Spiro[1,3-Dioxolane-4,3-[7]Oxabicyclo[4.1.0]Heptane]-2,2-Dione, 5-Hydroxy-, (1R,5S,6R)- (9Ci) is manufactured and analyzed under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.