Description

2H-Pyran-2-One,Tetrahydro-4,5-Dimethyl-6-(1-Methylethyl)-,(4R,5S,6R)-Rel-(9Ci) is a high-purity, stereochemically defined lactone compound valued for its role as a versatile chiral building block and flavor/fragrance intermediate. Its specific stereochemistry is critical for applications requiring precise molecular interaction, such as in asymmetric synthesis and the development of high-value organoleptic compounds. This product is essential for research and development chemists, flavor & fragrance houses, and pharmaceutical companies seeking reliable, high-quality chiral synthons.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs) where its defined stereocenters are crucial for biological activity.
• Flavor and Fragrance Ingredient: Serves as a key intermediate or precursor for creating complex, natural-tasting flavor notes and sophisticated fragrance molecules.
• Asymmetric Catalysis & Ligand Synthesis: Employed as a starting material for synthesizing chiral ligands and catalysts used in enantioselective transformations.
• Advanced Material Research: Investigated for potential use in the synthesis of specialty polymers or liquid crystals due to its rigid, functionalized structure.
• Agrochemical Intermediate: Utilized in the development of novel, stereospecific crop protection agents and pesticides.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic synthesis and for exploring new chemical spaces in discovery chemistry.

Basic Information

Product Name	2H-Pyran-2-One,Tetrahydro-4,5-Dimethyl-6-(1-Methylethyl)-,(4R,5S,6R)-Rel-(9Ci)
CAS No.	648434-45-1
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	rel-(4R,5S,6R)-4,5-Dimethyl-6-(1-methylethyl)tetrahydro-2H-pyran-2-one; Tetrahydro-4,5-dimethyl-6-(1-methylethyl)-2H-pyran-2-one, (4R,5S,6R)-rel-; (rel)-(4R,5S,6R)-4,5-Dimethyl-6-isopropyltetrahydro-2H-pyran-2-one; 6-Isopropyl-4,5-dimethyltetrahydro-2H-pyran-2-one (stereoisomer); Chiral Lactone Intermediate 648434-45-1
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Every batch of 2H-Pyran-2-One,Tetrahydro-4,5-Dimethyl-6-(1-Methylethyl)-,(4R,5S,6R)-Rel-(9Ci) is analyzed to ensure high chemical and stereochemical purity, typically meeting standards suitable for research and fine chemical synthesis. Certificates of Analysis (COA) detailing identity, purity (by HPLC/GC), chiral purity, and impurity profiles are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.