Description

2H-Pyran-2-One,Tetrahydro-3,4-Dimethyl-6-(1-Methylethyl)-,(3R,4R,6S)-Rel-(9Ci) is a high-purity, stereochemically defined lactone compound. This specific isomer is valued for its role as a critical chiral building block and flavor/fragrance intermediate in advanced chemical synthesis. It is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to produce enantiomerically pure products. The compound, CAS NO 648434-41-7, offers a reliable foundation for complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in stereoselective synthesis.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Flavor & Fragrance Ingredient: Acts as a precursor for creating complex, natural-identical lactone notes in perfumery and flavor compositions.
• Fine Chemical Building Block: Employed in organic research and development for constructing complex natural products and specialty molecules.
• Ligand and Catalyst Development: Utilized in the synthesis of chiral ligands and organocatalysts for asymmetric catalysis.

Basic Information

Product Name	2H-Pyran-2-One,Tetrahydro-3,4-Dimethyl-6-(1-Methylethyl)-,(3R,4R,6S)-Rel-(9Ci)
CAS No.	648434-41-7
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	(3R,4R,6S)-3,4-Dimethyl-6-(propan-2-yl)tetrahydro-2H-pyran-2-one; rel-(3R,4R,6S)-3,4-Dimethyl-6-isopropyltetrahydro-2H-pyran-2-one; 6-Isopropyl-3,4-dimethyltetrahydro-2H-pyran-2-one; Tetrahydro-3,4-dimethyl-6-(1-methylethyl)-2H-pyran-2-one; A stereoisomer of whisky lactone; Oak lactone isomer.
EINECS	Contact for details

Quality Control

Every batch of our (3R,4R,6S)-Rel- Tetrahydro-3,4-dimethyl-6-isopropyl-2H-pyran-2-one is produced under a strict quality management system. We provide comprehensive analytical data to ensure high chiral purity and chemical identity, critical for your sensitive synthesis processes. Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are available upon request and are backed by analytical techniques including HPLC, GC, and chiral chromatography.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.