Description

6-Methyl-Nicotinic Acid 2,5-Dioxo-Pyrrolidin-1-Yl Ester is a high-purity, reactive chemical intermediate belonging to the class of activated esters. This compound is specifically designed for efficient amide bond formation, offering significant advantages in synthetic chemistry workflows. It is an essential building block for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key reagent for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via peptide coupling and amidation reactions.
• Bioconjugation: Used in the modification of biomolecules, such as proteins and peptides, for drug delivery systems and diagnostic applications.
• Agrochemical Synthesis: Serves as a building block in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Employed in the creation of functionalized polymers and specialty materials with tailored properties.
• Organic Synthesis Research: A versatile tool in academic and industrial R&D for constructing amide linkages under mild conditions.
• Peptide Mimetics: Facilitates the synthesis of peptidomimetics and other bioactive compounds in medicinal chemistry.

Basic Information

Product Name	6-Methyl-Nicotinic Acid 2,5-Dioxo-Pyrrolidin-1-Yl Ester
CAS No.	648422-42-8
Molecular Formula	C12H10N2O4
Molecular Weight	246.22 g/mol
Synonyms	6-Methylnicotinic Acid N-Hydroxysuccinimide Ester; 6-Methylpyridine-3-carboxylic Acid 2,5-Dioxopyrrolidin-1-yl Ester; 1-[(6-Methyl-3-pyridinyl)carbonyloxy]-2,5-pyrrolidinedione; 6-Methylnicotinic Acid NHS Ester; 6-Methylnicotinoyloxysuccinimide; 3-Carboxy-6-methylpyridine N-succinimidyl ester; 6-Methyl-3-pyridinecarboxylic acid succinimidyl ester; N-Succinimidyl 6-methylnicotinate
EINECS	Contact for details

Quality Control

Our 6-Methyl-Nicotinic Acid 2,5-Dioxo-Pyrrolidin-1-Yl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.