Description

Trilobatin 2''-Acetate is a specialized acetylated derivative of the natural sweetener trilobatin, offering enhanced properties for research and development. This high-purity compound is critical for applications requiring precise molecular modification and structure-activity relationship (SAR) studies. It serves as a valuable intermediate and reference standard for pharmaceutical, nutraceutical, and flavor research scientists focused on sweet taste receptor modulation and novel sweetener development.

Application

• Pharmaceutical Research: Key intermediate in the synthesis and development of novel non-caloric sweeteners and taste modulators.
• Flavor & Fragrance Industry: Used in R&D for creating and analyzing modified sweetening agents with improved stability or sensory profiles.
• Nutraceutical Development: Serves as a reference compound in the study of natural sweetener derivatives for functional food and beverage applications.
• Academic & Biochemical Research: Essential for studying glycoside biochemistry, enzymatic acetylation, and sweet taste receptor (T1R2/T1R3) interactions.
• Analytical Standard: High-purity grade used as a chromatographic reference standard (HPLC, LC-MS) for quality control and method development.
• Process Chemistry: Employed in scaling up synthetic pathways for derivative libraries in drug discovery programs.

Basic Information

Product Name	Trilobatin 2''-Acetate
CAS No.	647853-82-5
Molecular Formula	C23H26O11
Molecular Weight	478.45 g/mol
Synonyms	Phloridzin 2''-Acetate; Trilobatin acetate; 4',6-Dihydroxy-2'-(3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-(3,4-dihydroxyphenyl)propiophenone 2''-acetate; 2''-O-Acetyltrilobatin; Phloretin 2'-O-glucoside 2''-acetate; 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxy-3-(3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)phenyl)propan-1-one 2''-acetate
EINECS	Contact for details

Quality Control

Our Trilobatin 2''-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure it meets high-purity research standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.