Description

Cyclopentanecarboxylic Acid, 2-Amino-3-Methyl-, 1,1-Dimethylethyl Ester is a high-purity, protected amino acid derivative serving as a critical chiral building block in advanced organic synthesis. This compound is essential for the development of complex molecules, offering a sterically hindered tert-butyl ester group that provides excellent stability during multi-step synthetic sequences. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals, where precise stereochemistry and reliable purity are paramount. CAS NO 646518-10-7.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for peptidomimetics and small molecule drugs.
• Agrochemical Synthesis: Used in the construction of complex, biologically active molecules for crop protection and pesticide development.
• Peptide Chemistry: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis, enabling the incorporation of constrained cyclopentane motifs.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial R&D: A valuable tool for chemists in both academic and industrial settings exploring new chemical spaces and molecular architectures.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Amino-3-Methyl-, 1,1-Dimethylethyl Ester
CAS No.	646518-10-7
Molecular Formula	C12H23NO2
Molecular Weight	213.32 g/mol
Synonyms	tert-Butyl 2-amino-3-methylcyclopentanecarboxylate; 2-Amino-3-methylcyclopentanecarboxylic acid tert-butyl ester; 1,1-Dimethylethyl 2-amino-3-methyl-1-cyclopentanecarboxylate; 2-Amino-3-methylcyclopentane-1-carboxylic acid tert-butyl ester; (1R,2S,3R)-2-Amino-3-methylcyclopentanecarboxylic acid tert-butyl ester (for specific stereoisomer); tert-Butyl (2-amino-3-methylcyclopentyl)carboxylate; Boc-AMCP (if used as a protected amino acid analog); 646518-10-7
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-Amino-3-Methyl-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/GC), chiral excess, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.