Description

3-Bromo-1-(4-[5-(Trifluoromethyl)Pyridin-2-Yl]-1,4-Diazepan-1-Yl)Propan-1-One is a high-value, specialized organic intermediate featuring a unique heterocyclic diazepane scaffold linked to a trifluoromethylpyridine moiety. This compound matters for its role as a critical building block in modern pharmaceutical and agrochemical research, enabling the synthesis of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for creating new drug candidates and functional chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the trifluoromethylpyridine group.
• Chemical Biology Probe Development: Acts as a scaffold for creating tool compounds to study biological pathways and protein functions.
• Material Science: Potential building block for advanced organic materials, such as ligands for catalysts or components in organic electronics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-Bromo-1-(4-[5-(Trifluoromethyl)Pyridin-2-Yl]-1,4-Diazepan-1-Yl)Propan-1-One
CAS No.	646455-90-5
Molecular Formula	C14H15BrF3N3O
Molecular Weight	378.19 g/mol
Synonyms	1-(4-(5-(Trifluoromethyl)pyridin-2-yl)-1,4-diazepan-1-yl)-3-bromopropan-1-one; 3-Bromo-1-[4-[5-(trifluoromethyl)-2-pyridinyl]-1,4-diazepan-1-yl]-1-propanone; 646455-90-5; 3-Bromo-1-(4-(5-(trifluoromethyl)pyridin-2-yl)-1,4-diazepan-1-yl)propan-1-one; Propan-1-one, 3-bromo-1-[4-[5-(trifluoromethyl)-2-pyridinyl]-1,4-diazepan-1-yl]-
EINECS	Contact for details

Quality Control

Our 3-Bromo-1-(4-[5-(Trifluoromethyl)Pyridin-2-Yl]-1,4-Diazepan-1-Yl)Propan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.