Description

Spiro[1-Azabicyclo[2.2.2]Octane-2,3-Pyrrolidine] (9Ci) is a complex, nitrogen-containing spirocyclic compound with a unique bridged bicyclic structure. This compound matters as a sophisticated chemical building block, enabling the synthesis of novel molecular architectures with potential for high biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Agrochemical Research: Used in the development of new crop protection agents and pesticides due to its complex, bioactive scaffold.
• Chemical Biology Probe: Acts as a core structure for designing molecular probes to study enzyme function and receptor interactions.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & R&D: A valuable compound for methodological research in organic synthesis and heterocyclic chemistry at universities and corporate R&D centers.

Basic Information

Product Name	Spiro[1-Azabicyclo[2.2.2]Octane-2,3-Pyrrolidine] (9Ci)
CAS No.	646055-90-5
Molecular Formula	C9H14N2
Molecular Weight	150.22 g/mol
Synonyms	Spiro[1-azabicyclo[2.2.2]octane-2,3'-pyrrolidine]; 1-Azaspiro[bicyclo[2.2.2]octane-2,3'-pyrrolidine]; 2,3-Pyrrolidinoquinuclidine; 646055-90-5; Spiro(quinuclidine-2,3'-pyrrolidine)
EINECS	Contact for details

Quality Control

Our Spiro[1-Azabicyclo[2.2.2]Octane-2,3-Pyrrolidine] (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.