Description

5'-Bromo-1',2'-Dihydrospiro[Cyclohexane-1,3'-Indole] is a sophisticated spirocyclic indole derivative, a high-value building block prized for its unique three-dimensional molecular architecture. This compound is critical for medicinal chemistry research and development, enabling the exploration of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on creating new therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery programs.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex molecular libraries for high-throughput screening (HTS).
• CNS Drug Discovery: Exploration of potential therapeutics for neurological disorders due to the privileged indole-spirocyclic structure.
• Oncology Research: Serves as a precursor in the development of potential kinase inhibitors and other targeted cancer therapies.
• Chemical Biology Probes: Utilized in the design of molecular probes to study protein function and biological mechanisms.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to create other high-value, complex organic molecules.

Basic Information

Product Name	5'-Bromo-1',2'-Dihydrospiro[Cyclohexane-1,3'-Indole]
CAS No.	645416-98-4
Molecular Formula	C14H16BrN
Molecular Weight	278.19 g/mol
Synonyms	5'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]; 5-Bromospiro[cyclohexane-1,3'-indoline]; 5-Bromo-1,2-dihydrospiro[3H-indole-3,1'-cyclohexane]; 5-Bromospiro[indoline-3,1'-cyclohexane]; 645416-98-4; Spiro[cyclohexane-1,3'-indole], 5'-bromo-1',2'-dihydro-
EINECS	Contact for details

Quality Control

Our 5'-Bromo-1',2'-Dihydrospiro[Cyclohexane-1,3'-Indole] is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical R&D, including compliance with relevant ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.