Description

2H-Pyran-2-Propanol,5-Fluorotetrahydro-,(2R,5R)-Rel-(9Ci) is a chiral fluorinated pyran derivative, a high-value synthetic intermediate of significant interest in advanced organic synthesis. Its precise stereochemistry and fluorine substitution make it a critical building block for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the development of advanced, fluorinated pesticides and herbicides where the fluorine atom enhances bioavailability and stability.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the study and development of new stereoselective catalytic reactions.
• Fluorine Chemistry Studies: Employed as a model compound in academic and industrial research exploring the effects of fluorine introduction on molecular properties.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various high-tech applications.

Basic Information

Product Name	2H-Pyran-2-Propanol,5-Fluorotetrahydro-,(2R,5R)-Rel-(9Ci)
CAS No.	645413-16-7
Molecular Formula	C8H13FO2
Molecular Weight	160.18 g/mol
Synonyms	(2R,5R)-5-Fluorotetrahydro-2H-pyran-2-propanol; rel-(2R,5R)-5-Fluorotetrahydro-2H-pyran-2-propanol; 5-Fluorotetrahydro-2H-pyran-2-propanol, (2R,5R)-rel-; (2R,5R)-rel-5-Fluorotetrahydro-2H-pyran-2-propanol; 645413-16-7; 2H-Pyran-2-propanol, 5-fluorotetrahydro-, (2R,5R)-rel-; Fluorinated Pyran Propanol Isomer
EINECS	Contact for details

Quality Control

Every batch of 2H-Pyran-2-Propanol,5-Fluorotetrahydro-,(2R,5R)-Rel-(9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques including chiral HPLC, GC, NMR, and MS to ensure high enantiomeric purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with each shipment to support your R&D and cGMP-compliant workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.