Description

Imidazo[1,2-A]Pyridine-6,7,8-Triol, 5,6,7,8-Tetrahydro-5-(Hydroxymethyl)-2-Methyl-, (5R,6R,7S,8R)- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly in modern drug discovery. It is primarily needed by research institutions and pharmaceutical companies engaged in developing novel therapeutics, where its specific stereochemistry and functional groups are essential for creating targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for complex heterocyclic compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for various therapeutic targets.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing more complex polycyclic or functionalized molecular architectures in fine chemical synthesis.
• Biochemical Research: Potential use as a probe or ligand in biochemical assays due to its specific structural features.
• Asymmetric Synthesis: Utilized in catalytic asymmetric reactions to introduce multiple chiral centers into target molecules.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine-6,7,8-Triol, 5,6,7,8-Tetrahydro-5-(Hydroxymethyl)-2-Methyl-, (5R,6R,7S,8R)- (9Ci)
CAS No.	644965-55-9
Molecular Formula	C9H14N2O4
Molecular Weight	214.22 g/mol
Synonyms	(5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)-2-methylimidazo[1,2-a]pyridine-6,7,8-triol; 5,6,7,8-Tetrahydro-5-(hydroxymethyl)-2-methylimidazo[1,2-a]pyridine-6,7,8-triol, (5R,6R,7S,8R)-; Imidazo[1,2-a]pyridine-6,7,8-triol, 5,6,7,8-tetrahydro-5-(hydroxymethyl)-2-methyl-, (5R,6R,7S,8R)-; CAS 644965-55-9; (5R,6R,7S,8R)-5-(Hydroxymethyl)-2-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-6,7,8-triol
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-A]Pyridine-6,7,8-Triol intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (5R,6R,7S,8R)-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.