Description

5-[4-[n-(2-Pyridylamino)Ethoxy]Benzylidene]Thiazolidine-2,4-Dione CAS NO 643764-88-9 is a high-purity, synthetic organic compound belonging to the thiazolidinedione class, recognized for its role as a key pharmaceutical intermediate and research chemical. This compound is valued for its structural complexity and its utility in the development of novel therapeutic agents targeting metabolic and inflammatory pathways. It is primarily required by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in drug discovery and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel thiazolidinedione-based drug candidates.
• Biochemical Research: Used as a reference standard and active probe in metabolic disease research, particularly studies related to PPAR (Peroxisome Proliferator-Activated Receptor) modulation.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies and biological mechanisms.

Basic Information

Product Name	5-[4-[n-(2-Pyridylamino)Ethoxy]Benzylidene]Thiazolidine-2,4-Dione
CAS No.	643764-88-9
Molecular Formula	C₁₇H₁₅N₃O₃S
Molecular Weight	341.39 g/mol
Synonyms	5-[[4-[2-(2-Pyridinylamino)ethoxy]phenyl]methylene]-2,4-thiazolidinedione; 5-((4-((2-(Pyridin-2-ylamino)ethoxy)benzylidene)thiazolidine-2,4-dione; (5Z)-5-[[4-[2-(Pyridin-2-ylamino)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione; TZD Derivative; PPARγ Modulator Intermediate; CAS 643764-88-9
EINECS	Contact for details

Quality Control

Our 5-[4-[n-(2-Pyridylamino)Ethoxy]Benzylidene]Thiazolidine-2,4-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and purity, and is supported by a detailed Certificate of Analysis (COA). We adhere to relevant industry standards for research-grade and pharmaceutical intermediate materials to support your critical R&D and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.