Description

3-Bromo-2-Bromomethyl-6-Fluoropyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents, makes it an invaluable intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel pyridine-based ligands used in transition metal catalysis and material science.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and route scouting.
• Functional Material Precursor: Potential intermediate in the synthesis of organic electronic materials, such as ligands for OLEDs or molecular sensors.

Basic Information

Product Name	3-Bromo-2-Bromomethyl-6-Fluoropyridine
CAS No.	643762-61-2
Molecular Formula	C6H4Br2FN
Molecular Weight	268.91 g/mol
Synonyms	2-(Bromomethyl)-3-bromo-6-fluoropyridine; 6-Fluoro-3-bromo-2-bromomethylpyridine; 3-Bromo-2-(bromomethyl)-6-fluoropyridine; Pyridine, 3-bromo-2-(bromomethyl)-6-fluoro-; 643762-61-2; 2,3-Dibromo-6-fluoromethylpyridine (common misnomer); 6-Fluoro-2,3-dibromomethylpyridine (common misnomer)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Bromomethyl-6-Fluoropyridine is manufactured under strict quality management protocols. We provide comprehensive analytical documentation to ensure traceability and consistency. Our standard quality commitment includes rigorous testing by HPLC, NMR, and GC-MS to confirm identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.