Description

1-(4-Fluorophenyl)-n-(6-Methylpyridin-2-Yl)-5-Oxopyrrolidine-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a key structural motif for targeting specific biological pathways. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Development: Serves as a precursor in the multi-step synthesis of potential active pharmaceutical ingredients.
• Biochemical Research: Employed as a tool compound or ligand in biochemical assays and target validation studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Used in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Product Name	1-(4-Fluorophenyl)-n-(6-Methylpyridin-2-Yl)-5-Oxopyrrolidine-3-Carboxamide
CAS No.	643731-93-5
Molecular Formula	C17H16FN3O2
Molecular Weight	313.33 g/mol
Synonyms	1-(4-Fluorophenyl)-N-(6-methylpyridin-2-yl)-5-oxopyrrolidine-3-carboxamide; 5-Oxo-1-(4-fluorophenyl)-N-(6-methyl-2-pyridinyl)-3-pyrrolidinecarboxamide; 1-(4-Fluorophenyl)-N-(6-methyl-2-pyridinyl)-5-oxo-3-pyrrolidinecarboxamide; 3-Carbamoyl-1-(4-fluorophenyl)-5-oxopyrrolidine-2-carboxylic acid (related); 643731-93-5; Fluorophenyl-methylpyridinyl-oxopyrrolidine carboxamide
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-n-(6-Methylpyridin-2-Yl)-5-Oxopyrrolidine-3-Carboxamide adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development and cGMP-grade requirements, with specifications tailored to meet the rigorous standards of pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.