Description

Benzyl n-Boc-3-Amino-5-Iodopentanoate CAS NO 643044-91-1 is a protected amino acid derivative featuring both a tert-butyloxycarbonyl (Boc) protecting group and a benzyl ester. This compound is a crucial high-purity building block in organic synthesis, designed to facilitate the controlled construction of complex peptide and small molecule targets. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for developing novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide-based drug candidates and other bioactive molecules.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate modified amino acid residues.
• Protecting Group Strategy: The Boc group provides orthogonal protection for the amine functionality, allowing for selective deprotection in multi-step syntheses.
• Cross-Coupling Reactions: The iodine substituent serves as a handle for further functionalization via palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Biology Probes: Synthesis of labeled or tagged peptides for research in proteomics and molecular imaging.
• Academic & Industrial Research: A versatile reagent for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	Benzyl n-Boc-3-Amino-5-Iodopentanoate
CAS No.	643044-91-1
Molecular Formula	C17H24INO4
Molecular Weight	433.28 g/mol
Synonyms	Benzyl 3-[(tert-Butoxycarbonyl)amino]-5-iodopentanoate; 5-Iodo-3-[(tert-butoxycarbonyl)amino]pentanoic Acid Benzyl Ester; Boc-3-Amino-5-iodopentanoic Acid Benzyl Ester; N-Boc-3-Amino-5-iodopentanoic Acid Benzyl Ester; Benzyl N-Boc-3-amino-5-iodovalerate; (3-{[(2-Methylpropan-2-yl)oxycarbonyl]amino}-5-iodopentyl) Benzoate; 643044-91-1
EINECS	Contact for details

Quality Control

Our Benzyl n-Boc-3-Amino-5-Iodopentanoate is manufactured under strict quality control protocols to ensure high chemical purity and lot-to-lot consistency, suitable for sensitive synthetic applications. All batches are characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.