Description

Azido-Peg4-Nhboc is a heterobifunctional polyethylene glycol (PEG) crosslinker featuring an azide group and a tert-butyloxycarbonyl (Boc)-protected amine. This compound is essential for creating stable, biocompatible conjugates in advanced bioconjugation and materials science applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostics industries for the development of antibody-drug conjugates (ADCs), peptide modifications, and hydrogel networks.

Application

• Bioconjugation & ADC Development: Enables site-specific "click chemistry" conjugation via its azide group to alkynes on drug molecules, antibodies, or proteins.
• Peptide & Protein Modification: Serves as a versatile spacer to introduce PEG chains, improving solubility, stability, and pharmacokinetic properties of therapeutic peptides.
• Polymer & Materials Science: Acts as a functional building block for synthesizing smart polymers, hydrogels, and surface coatings with tailored properties.
• Diagnostic Probe Synthesis: Used to attach targeting ligands or fluorophores to nanoparticles or other diagnostic platforms.
• Chemical Biology Tool: Facilitates the study of biomolecular interactions and cellular processes through controlled labeling and crosslinking.
• Drug Delivery Systems: Incorporated into nanocarrier designs to create stimuli-responsive or targeted delivery vehicles.

Basic Information

Product Name	Azido-Peg4-Nhboc
CAS No.	642091-68-7
Molecular Formula	C20H38N4O8
Molecular Weight	462.54 g/mol
Synonyms	1-Azido-3,6,9,12-tetraoxapentadecan-15-amine, N-Boc; 15-Amino-4,7,10,13-tetraoxa-1-azapentadecane-1-azide, N-Boc; Boc-NH-PEG4-Azide; Boc-Amine-PEG4-Azide; N-(tert-Butoxycarbonyl)-3,6,9,12-tetraoxa-15-azapentadecane-15-amine, 1-azide; Azido-PEG4-amine-Boc; Heterobifunctional PEG crosslinker, Azide-PEG4-NHBoc
EINECS	Contact for details

Quality Control

Our Azido-Peg4-Nhboc is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your research and cGMP development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under desiccant to maintain long-term stability. The product is moisture-sensitive and should be handled under inert atmosphere when possible to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.