Description

2-(4-Bromophenyl)-Propanedioic Acid 1,3-Bis-T-Butyl Ester is a high-purity, protected malonate derivative, a critical building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers in the fine chemical, pharmaceutical, and advanced material sectors who require reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing a bromophenyl moiety or malonate-derived structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive diester functionality.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and other C-C bond-forming processes to create complex organic molecules.
• Material Science Research: Serves as a monomer or precursor in the development of specialized polymers and advanced organic materials.
• Academic & R&D Laboratories: A valuable reagent for methodological development and the synthesis of novel chemical entities in research settings.

Basic Information

Product Name	2-(4-Bromophenyl)-Propanedioic Acid 1,3-Bis-T-Butyl Ester
CAS No.	641638-37-1
Molecular Formula	C₁₇H₂₃BrO₄
Molecular Weight	371.27 g/mol
Synonyms	Di-tert-butyl 2-(4-bromophenyl)malonate; 1,3-Bis(1,1-dimethylethyl) 2-(4-bromophenyl)-1,3-propanedioate; 2-(4-Bromophenyl)malonic Acid Di-tert-butyl Ester; Propanedioic acid, 2-(4-bromophenyl)-, 1,3-bis(1,1-dimethylethyl) ester; Di-t-butyl (4-bromophenyl)malonate; (4-Bromophenyl)malonic Acid Di-tert-butyl Ester
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-Propanedioic Acid 1,3-Bis-T-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.