Description

5-(4-Fluorophenyl)-3-Nitro-2-Pyridinylamine is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyridine-based structure with fluorophenyl and nitro substituents. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its fluorinated aromatic system for bioactivity.
• Material Science Precursor: Serves as a starting material for creating specialized ligands, catalysts, and functionalized polymers.
• Academic & Contract Research: Essential for methodological studies in organic synthesis, heterocyclic chemistry, and structure-activity relationship (SAR) investigations.

Basic Information

Product Name	5-(4-Fluorophenyl)-3-Nitro-2-Pyridinylamine
CAS No.	640271-51-8
Molecular Formula	C11H8FN3O2
Molecular Weight	233.20 g/mol
Synonyms	2-Amino-5-(4-fluorophenyl)-3-nitropyridine; 5-(4-Fluorophenyl)-3-nitro-2-pyridinamine; 3-Nitro-5-(4-fluorophenyl)pyridin-2-amine; 2-Pyridinamine, 5-(4-fluorophenyl)-3-nitro-; 5-(p-Fluorophenyl)-3-nitro-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)-3-Nitro-2-Pyridinylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.