Description

2-Phenyl-3-(Trifluoromethyl)-Pyridine is a high-value, multi-functional heterocyclic building block characterized by its phenyl and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the trifluoromethyl group can significantly enhance metabolic stability and lipophilicity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides, where the trifluoromethyl group contributes to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organic synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on the incorporation and effects of fluorine atoms in molecular structures.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for use in bespoke synthesis projects for client-specific molecules.

Basic Information

Product Name	2-Phenyl-3-(Trifluoromethyl)-Pyridine
CAS No.	639782-24-4
Molecular Formula	C12H8F3N
Molecular Weight	223.20 g/mol
Synonyms	3-(Trifluoromethyl)-2-phenylpyridine; 2-Phenyl-3-(trifluoromethyl)pyridine; 2-Phenyl-3-trifluoromethylpyridine; Pyridine, 2-phenyl-3-(trifluoromethyl)-; 639782-24-4; α-Phenyl-β-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Phenyl-3-(Trifluoromethyl)-Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.