Description

6-Amino-3-(2-Fluorobenzyl)-1H-Pyrimidine-2,4-Dione is a high-purity, fluorinated pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential therapeutic agents targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially in oncology and antiviral therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Biochemical Research: May be utilized as a substrate or inhibitor in enzymatic studies due to its pyrimidine-2,4-dione core structure.
• Agrochemical Development: Potential intermediate in the synthesis of novel herbicides or plant growth regulators.

Basic Information

Product Name	6-Amino-3-(2-Fluorobenzyl)-1H-Pyrimidine-2,4-Dione
CAS No.	639780-60-2
Molecular Formula	C11H10FN3O2
Molecular Weight	235.22 g/mol
Synonyms	6-Amino-3-[(2-fluorophenyl)methyl]-1H-pyrimidine-2,4-dione; 3-(2-Fluorobenzyl)-6-aminouracil; 6-Amino-1H-pyrimidine-2,4-dione, 3-[(2-fluorophenyl)methyl]-; 6-Amino-3-(2-fluorobenzyl)uracil; 2,4(1H,3H)-Pyrimidinedione, 6-amino-3-[(2-fluorophenyl)methyl]-; 639780-60-2; 3-(2-Fluorobenzyl)-6-aminopyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 6-Amino-3-(2-Fluorobenzyl)-1H-Pyrimidine-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.