Description

3-(3-Bromopyrid-5-Yl)-Propenoic Acid is a high-purity brominated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures through cross-coupling and functional group transformations. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and photoactive compounds due to its conjugated system.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	3-(3-Bromopyrid-5-Yl)-Propenoic Acid
CAS No.	638220-12-9
Molecular Formula	C8H6BrNO2
Molecular Weight	228.05 g/mol
Synonyms	(E)-3-(5-Bromopyridin-3-yl)acrylic acid; 3-(5-Bromo-3-pyridinyl)-2-propenoic acid; 5-Bromo-3-pyridineacrylic acid; trans-3-(5-Bromopyridin-3-yl)acrylic acid; 3-(5-Bromopyridin-3-yl)prop-2-enoic acid; 3-(3-Bromo-5-pyridyl)acrylic acid; 2-Propenoic acid, 3-(5-bromo-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 3-(3-Bromopyrid-5-Yl)-Propenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.