Description

n-(5-Bromo-6-Methyl-2-Pyridinyl)-4-Fluorobenzamide is a high-purity, advanced pharmaceutical intermediate with a distinct halogenated pyridine-benzamide structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel drug candidates, especially in oncology and CNS disorder research pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Organic Synthesis: Employed in cross-coupling reactions and as a precursor for more complex heterocyclic compounds due to its reactive bromo and amide functionalities.
• Biochemical Research: Potential use as a probe or ligand in biochemical assays studying protein-ligand interactions.

Basic Information

Product Name	n-(5-Bromo-6-Methyl-2-Pyridinyl)-4-Fluorobenzamide
CAS No.	638141-92-1
Molecular Formula	C13H10BrFN2O
Molecular Weight	309.14 g/mol
Synonyms	4-Fluoro-N-(5-bromo-6-methyl-2-pyridinyl)benzamide; 4-Fluoro-N-(5-bromo-6-methylpyridin-2-yl)benzamide; 5-Bromo-6-methyl-2-pyridinamine, N-(4-fluorobenzoyl)-; Benzamide, N-(5-bromo-6-methyl-2-pyridinyl)-4-fluoro-; 638141-92-1; 4-Fluorobenzoic acid (5-bromo-6-methyl-2-pyridinyl)amide
EINECS	Contact for details

Quality Control

Our n-(5-Bromo-6-Methyl-2-Pyridinyl)-4-Fluorobenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.