Description

Di-Tert.-Butyl 4-Chloro-2,6-Pyridinedicarboxylate CAS NO 638128-19-5 is a high-purity, protected pyridinedicarboxylate derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and fine chemical synthesis where precise functional group manipulation is required. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing complex pyridine cores.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides that require halogenated pyridine motifs.
• Ligand and Catalyst Preparation: Serves as a precursor for the synthesis of specialized ligands used in coordination chemistry and catalytic systems.
• Material Science Research: Employed in the creation of organic semiconductors, metal-organic frameworks (MOFs), and other functional organic materials.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic and Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical reactions involving sterically hindered esters.

Basic Information

Item	Detail
Product Name	Di-Tert.-Butyl 4-Chloro-2,6-Pyridinedicarboxylate
CAS No.	638128-19-5
Molecular Formula	C15H20ClNO4
Molecular Weight	313.78 g/mol
Synonyms	4-Chloro-2,6-pyridinedicarboxylic Acid Di-tert-butyl Ester; Di-tert-butyl 4-chloropyridine-2,6-dicarboxylate; 2,6-Bis(tert-butoxycarbonyl)-4-chloropyridine; 4-Chloro-2,6-di-tert-butoxycarbonylpyridine; 4-Chloropyridine-2,6-dicarboxylic Acid Di-tert-butyl Ester; tert-Butyl 4-chloro-2,6-pyridinedicarboxylate
EINECS	Contact for details

Quality Control

Our Di-Tert.-Butyl 4-Chloro-2,6-Pyridinedicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards where required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.