Description

2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine is a high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a bromine substituent and a trifluoromethylphenyl group, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for the synthesis of specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, such as those used in OLEDs or semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine
CAS No.	637352-38-6
Molecular Formula	C12H7BrF3N
Molecular Weight	302.09 g/mol
Synonyms	2-Bromo-6-[4-(trifluoromethyl)phenyl]pyridine; 6-Bromo-2-(4-trifluoromethylphenyl)pyridine; 2-Bromo-6-(4-trifluoromethylphenyl)pyridine; [4-(6-Bromopyridin-2-yl)phenyl]trifluoromethane; 2-(4-Trifluoromethylphenyl)-6-bromopyridine; 637352-38-6; 2-Bromo-6-(alpha,alpha,α-trifluoro-p-tolyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine is manufactured and tested under a strict quality management system. We guarantee high-purity material suitable for demanding research and scale-up applications. Comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, is performed to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.