Description

3-Bromo-2-Hydroxy-5-Iodopyridine is a high-purity halogenated pyridine derivative, serving as a critical multi-functional building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen functionalities into heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes due to its reactive halogen sites.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	3-Bromo-2-Hydroxy-5-Iodopyridine
CAS No.	637348-81-3
Molecular Formula	C5H3BrINO
Molecular Weight	299.89 g/mol
Synonyms	5-Iodo-3-bromo-2-hydroxypyridine; 3-Bromo-5-iodopyridin-2-ol; 2-Hydroxy-3-bromo-5-iodopyridine; 3-Bromo-5-iodo-2-pyridinol; 2-Pyridinol, 3-bromo-5-iodo-; 3-Bromo-5-iodo-2(1H)-pyridinone (tautomer); Halogenated pyridine intermediate; BIHIP
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Hydroxy-5-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.