Description

Methyl2-(2-Ethynylphenyl)Acetate CAS NO 637348-19-7 is a specialized aromatic ester building block featuring a reactive ethynyl group. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by material scientists developing specialty polymers and advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides with targeted modes of action.
• Material Science Research: Building block for creating advanced polymers, liquid crystals, and organic semiconductors (OLEDs, OFETs).
• Chemical Synthesis: Versatile precursor for Sonogashira coupling and other cross-coupling reactions to create complex conjugated systems.
• Academic & Industrial R&D: Essential reagent for exploratory chemistry in university laboratories and corporate innovation centers.

Basic Information

Product Name	Methyl2-(2-Ethynylphenyl)Acetate
CAS No.	637348-19-7
Molecular Formula	C11H10O2
Molecular Weight	174.20 g/mol
Synonyms	Methyl (2-ethynylphenyl)acetate; 2-Ethynylbenzeneacetic acid methyl ester; Methyl 2-(2-ethynylphenyl)ethanoate; (2-Ethynylphenyl)acetic acid methyl ester; Methyl α-(2-ethynylphenyl)acetate; Methyl o-ethynylphenylacetate
EINECS	Contact for details

Quality Control

Our Methyl2-(2-Ethynylphenyl)Acetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support custom synthesis and can tailor purity grades to meet specific R&D or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.