Description

3-Pyridinecarboxylic Acid, 2-(Chloromethyl)-6-(Trifluoromethyl)-, Ethyl Ester is a high-purity, multi-functional pyridine derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering a unique combination of reactive sites for targeted modifications. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging the trifluoromethyl group for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its aromatic core and halogen substituents.
• Custom Chemical Synthesis: Provides a versatile scaffold for contract research organizations (CROs) and fine chemical manufacturers to produce bespoke compounds for client projects.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 2-(Chloromethyl)-6-(Trifluoromethyl)-, Ethyl Ester
CAS No.	636588-26-6
Molecular Formula	C10H9ClF3NO2
Molecular Weight	267.63 g/mol
Synonyms	Ethyl 2-(Chloromethyl)-6-(trifluoromethyl)nicotinate; 2-(Chloromethyl)-6-(trifluoromethyl)nicotinic Acid Ethyl Ester; 2-(Chloromethyl)-6-(trifluoromethyl)-3-pyridinecarboxylic Acid Ethyl Ester; Nicotinic acid, 2-(chloromethyl)-6-(trifluoromethyl)-, ethyl ester; Ethyl 2-(chloromethyl)-6-(trifluoromethyl)pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarboxylic Acid, 2-(Chloromethyl)-6-(Trifluoromethyl)-, Ethyl Ester is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.