Description

Methyl 2-Amino-5-Bromo-3-Nitrobenzoate is a high-purity, multi-functional aromatic ester building block designed for advanced chemical synthesis. Its value lies in the strategic placement of reactive amino, bromo, and nitro functional groups on a benzoate core, enabling precise and sequential derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it serves as a critical intermediate for developing active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with specific modes of action.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and high-performance pigments due to its nitro and amino groups.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig amination.
• Chemical Library Development: A versatile scaffold for generating diverse compound libraries in medicinal chemistry and drug discovery programs.

Basic Information

Product Name	Methyl 2-Amino-5-Bromo-3-Nitrobenzoate
CAS No.	636581-61-8
Molecular Formula	C8H7BrN2O4
Molecular Weight	275.06 g/mol
Synonyms	Methyl 2-amino-5-bromo-3-nitrobenzoate; 2-Amino-5-bromo-3-nitrobenzoic acid methyl ester; Benzoic acid, 2-amino-5-bromo-3-nitro-, methyl ester; Methyl 5-bromo-2-amino-3-nitrobenzoate; 5-Bromo-2-amino-3-nitrobenzoic acid methyl ester; MBANB; CAS 636581-61-8
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Amino-5-Bromo-3-Nitrobenzoate is produced under strict quality management protocols. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your precise research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.