Description

2-Chloro-4-((4-Methoxybenzyl)Oxy)Nicotinonitrile is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. Its molecular structure, featuring a chloronicotinonitrile core and a methoxybenzyloxy protecting group, makes it a critical precursor for synthesizing complex heterocyclic compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, particularly those developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging its heterocyclic scaffold.
• Chemical Research & Development: Serves as a versatile precursor for constructing pyridine and nicotinonitrile derivatives in academic and industrial R&D labs.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring specific aromatic and heteroaromatic motifs.
• Ligand and Catalyst Development: Utilized for creating novel ligands and organocatalysts due to its potential metal-coordinating sites and modifiable functional groups.

Basic Information

Product Name	2-Chloro-4-((4-Methoxybenzyl)Oxy)Nicotinonitrile
CAS No.	635732-01-3
Molecular Formula	C14H11ClN2O2
Molecular Weight	274.70 g/mol
Synonyms	2-Chloro-4-[(4-methoxybenzyl)oxy]pyridine-3-carbonitrile; 3-Cyano-2-chloro-4-[(4-methoxybenzyl)oxy]pyridine; 2-Chloro-4-(4-methoxybenzyloxy)nicotinonitrile; 4-[(4-Methoxybenzyl)oxy]-2-chloro-3-pyridinecarbonitrile; 2-Chloro-4-(p-methoxybenzyloxy)nicotinonitrile; 2-Chloro-4-(PMB-oxy)nicotinonitrile; 2-Chloro-4-(4-methoxybenzyloxy)-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-((4-Methoxybenzyl)Oxy)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.