Description

2-Bromo-4-Hydroxynicotinonitrile is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial laboratories.
• Material Science: Potential building block for the synthesis of specialty polymers, ligands, or organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Bromo-4-Hydroxynicotinonitrile
CAS No.	635731-97-4
Molecular Formula	C6H3BrN2O
Molecular Weight	199.01 g/mol
Synonyms	4-Hydroxy-2-bromonicotinonitrile; 2-Bromo-4-hydroxypyridine-3-carbonitrile; 3-Cyano-2-bromo-4-hydroxypyridine; 2-Bromo-4-pyridinol-3-carbonitrile; Nicotinonitrile, 2-bromo-4-hydroxy-; 4-Hydroxy-2-bromo-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Hydroxynicotinonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.