Description

2-(3-(Trifluoromethyl)Phenyl)Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct trifluoromethylphenyl-substituted nicotinic acid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing next-generation small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in developing advanced herbicides and pesticides with improved efficacy and environmental profiles.
• Material Science: Serves as a precursor for functional materials, including liquid crystals and organic semiconductors.
• Chemical Synthesis: Versatile reagent for introducing the trifluoromethylphenyl moiety into complex organic molecules via coupling reactions.
• Academic & R&D: Essential reference standard and starting material for medicinal chemistry and organic synthesis research programs.

Basic Information

Product Name	2-(3-(Trifluoromethyl)Phenyl)Nicotinic Acid
CAS No.	635325-17-6
Molecular Formula	C13H8F3NO2
Molecular Weight	267.20 g/mol
Synonyms	2-[3-(Trifluoromethyl)phenyl]pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-[3-(trifluoromethyl)phenyl]-; Nicotinic acid, 2-(3-(trifluoromethyl)phenyl)-; 2-(3-Trifluoromethylphenyl)nicotinic acid; 635325-17-6; 2-(α,α,α-Trifluoro-m-tolyl)nicotinic acid
EINECS	Contact for details

Quality Control

Our 2-(3-(Trifluoromethyl)Phenyl)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with client specifications and relevant industry guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.