Description

(E)-3-Cyclopropyl-n-(1-(Pyridin-4-Yl)Ethylidene)-1H-Pyrazole-5-Carbohydrazide is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrazole-pyridine hybrid structure. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring complex heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Employed in the research and synthesis of novel pesticides and herbicides, leveraging its heterocyclic properties.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and enzyme functions.
• Academic & Institutional Research: A valuable reagent for universities and research institutes exploring new organic synthesis methodologies and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized, client-specific compounds.

Basic Information

Product Name	(E)-3-Cyclopropyl-n-(1-(Pyridin-4-Yl)Ethylidene)-1H-Pyrazole-5-Carbohydrazide
CAS No.	634884-24-5
Molecular Formula	C14H15N5O
Molecular Weight	269.30 g/mol
Synonyms	(E)-3-Cyclopropyl-N'-(1-(pyridin-4-yl)ethylidene)-1H-pyrazole-5-carbohydrazide; 3-Cyclopropyl-N-[(1E)-1-(4-pyridinyl)ethylidene]-1H-pyrazole-5-carbohydrazide; 1H-Pyrazole-5-carboxylic acid, 3-cyclopropyl-N-[(1E)-1-(4-pyridinyl)ethylidene]hydrazide; (E)-N'-(1-(Pyridin-4-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide; Pyrazole-Pyridine Hydrazide Derivative; CAS 634884-24-5
EINECS	Contact for details

Quality Control

Every batch of (E)-3-Cyclopropyl-n-(1-(Pyridin-4-Yl)Ethylidene)-1H-Pyrazole-5-Carbohydrazide undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.