Description

3-Iodo-1H-Pyrazolo[4,3-B]Pyridine is a high-value halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and agrochemicals, enabling critical carbon-carbon and carbon-heteroatom bond-forming reactions. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a starting material for creating specialized organic ligands and functionalized polymers with tailored electronic properties.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	3-Iodo-1H-Pyrazolo[4,3-B]Pyridine
CAS No.	633328-40-2
Molecular Formula	C6H4IN3
Molecular Weight	245.02 g/mol
Synonyms	3-Iodo-1H-pyrazolo[4,3-b]pyridine; 1H-Pyrazolo[4,3-b]pyridine, 3-iodo-; 3-Iodopyrazolo[4,3-b]pyridine; 3-Iodo-1H-pyrazolo[4,3-b]pyridine; 633328-40-2; 3-Iodo-1H-pyrazolo[4,3-b]pyridine; Pyrazolo[4,3-b]pyridine, 3-iodo-1H-
EINECS	Contact for details

Quality Control

Our 3-Iodo-1H-Pyrazolo[4,3-B]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of our global pharmaceutical and agrochemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.