Description

1H-Pyrazolo[4,3-B]Pyridine,3-Bromo-1-(Triphenylmethyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Organic Synthesis Building Block: Used in the construction of complex polyheterocyclic systems due to its reactive bromo and protected amine functionalities.
• Agrochemical Research: Potential application in the development of new active ingredients for crop protection.
• Material Science: Exploration of its use in the synthesis of organic electronic materials and ligands for catalysis.

Basic Information

Product Name	1H-Pyrazolo[4,3-B]Pyridine,3-Bromo-1-(Triphenylmethyl)-
CAS No.	633328-34-4
Molecular Formula	C25H18BrN3
Molecular Weight	440.34 g/mol
Synonyms	3-Bromo-1-trityl-1H-pyrazolo[4,3-b]pyridine; 3-Bromo-1-(triphenylmethyl)-1H-pyrazolo[4,3-b]pyridine; 1-(Triphenylmethyl)-3-bromo-1H-pyrazolo[4,3-b]pyridine; 3-Bromo-1-tritylpyrazolo[4,3-b]pyridine; 1-Trityl-3-bromo-1H-pyrazolo[4,3-b]pyridine; 3-Bromo-1-trityl-1H-pyrazolo[4,3-b]pyridin; 3-Bromo-1-trityl-1H-pyrazolo[4,3-b]pyridine (Trityl-protected bromo pyrazolopyridine)
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[4,3-B]Pyridine,3-Bromo-1-(Triphenylmethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.