Description

3,5-Dibromo-2-Fluoro-6-Methylpyridine is a high-purity halogenated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique substitution pattern, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce key halogenated motifs into active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated and brominated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its halogen atoms contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of specialty chemicals, ligands for catalysis, and functionalized organic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling complex bond formations.
• Fluorine Chemistry: The fluorine atom makes it a valuable probe in medicinal chemistry for studying bioavailability and binding interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects and scale-up development.

Basic Information

Product Name	3,5-Dibromo-2-Fluoro-6-Methylpyridine
CAS No.	632628-07-0
Molecular Formula	C6H4Br2FN
Molecular Weight	268.91 g/mol
Synonyms	2-Fluoro-3,5-dibromo-6-methylpyridine; 6-Methyl-3,5-dibromo-2-fluoropyridine; Pyridine, 3,5-dibromo-2-fluoro-6-methyl-; 3,5-Dibromo-2-fluoro-6-picoline
EINECS	Contact for details

Quality Control

Every batch of 3,5-Dibromo-2-Fluoro-6-Methylpyridine is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.