Description

tert-Butyl 4-Amino-3-Phenylpiperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile chiral scaffold with orthogonal protecting groups, enabling the efficient construction of complex pharmacologically active molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of central nervous system (CNS) active drugs, analgesics, and other therapeutic agents.
• Agrochemical Synthesis: Used in the creation of novel, high-performance crop protection agents and pesticides.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke, high-value fine chemicals.
• Academic Research: Utilized in university and institutional labs for developing new synthetic methodologies and exploring novel chemical spaces.

Basic Information

Product Name	tert-Butyl 4-Amino-3-Phenylpiperidine-1-Carboxylate
CAS No.	632352-60-4
Molecular Formula	C16H24N2O2
Molecular Weight	276.38 g/mol
Synonyms	1-Boc-4-amino-3-phenylpiperidine; 4-Amino-3-phenylpiperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-amino-3-phenyl-1-piperidinecarboxylate; 3-Phenyl-4-aminopiperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-4-amino-3-phenylpiperidine; 4-Amino-3-phenyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; Boc-4-Amino-3-phenylpiperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Amino-3-Phenylpiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.