Description

Benzene, 1-Bromo-3-Fluoro-2-(Trimethylsilyl)- is a high-value, multi-functional organosilicon intermediate with a unique halogenated aromatic structure. This compound is critical for advanced organic synthesis, particularly in the construction of complex molecules for pharmaceuticals and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for its role in cross-coupling reactions and as a building block for novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic or silyl-protected motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and silicon functionality.
• Material Science Precursor: Acts as a monomer or precursor for advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Reagent: Employed in laboratories for the selective introduction of bromo, fluoro, and trimethylsilyl groups into complex molecular architectures.
• Chemical Research: Utilized in academic and industrial R&D for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	Benzene, 1-Bromo-3-Fluoro-2-(Trimethylsilyl)-
CAS No.	632324-41-5
Molecular Formula	C9H12BrFSi
Molecular Weight	247.18 g/mol
Synonyms	1-Bromo-3-fluoro-2-(trimethylsilyl)benzene; 2-Bromo-6-fluoro-1-(trimethylsilyl)benzene; 2-Bromo-6-fluorophenyltrimethylsilane; (2-Bromo-6-fluorophenyl)trimethylsilane; Benzene, 1-bromo-3-fluoro-2-(trimethylsilyl)-; 1-Bromo-3-fluoro-2-trimethylsilylbenzene; 2-Bromo-6-fluoro-1-trimethylsilylbenzene
EINECS	Contact for details

Quality Control

Our production of Benzene, 1-Bromo-3-Fluoro-2-(Trimethylsilyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Purity (HPLC)	≥ 96.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.