Description

6-Bromo-5-Chloropyridine-3-Sulfonyl Chloride is a high-value, multi-functional heterocyclic building block and key synthetic intermediate. Its molecular structure, featuring both a sulfonyl chloride and halogen substituents, makes it a versatile electrophile for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists engaged in the synthesis of novel active ingredients, where it serves as a critical precursor for sulfonamide and sulfonate derivatives.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create new sulfonamide-based bioactive compounds.
• Material Science Research: Serves as a building block for creating functionalized polymers, ligands for catalysis, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Utilized as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	6-Bromo-5-Chloropyridine-3-Sulfonyl Chloride
CAS No.	631912-23-7
Molecular Formula	C5H2BrCl2NO2S
Molecular Weight	315.95 g/mol
Synonyms	3-Chlorosulfonyl-6-bromo-5-chloropyridine; 5-Chloro-6-bromopyridine-3-sulfonyl chloride; 6-Bromo-5-chloro-3-pyridinesulfonyl chloride; 6-Bromo-5-chloropyridine-3-sulfonylchloride; 3-Pyridinesulfonyl chloride, 6-bromo-5-chloro-; 5-Chloro-6-bromopyridine-3-sulfonylchloride
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Chloropyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.