Description

4-Cyclopropyl-3-Oxo-Butyric Acid Ethyl Ester is a high-purity, versatile β-keto ester building block essential for advanced organic synthesis. Its unique cyclopropyl and keto-ester functionalities make it a critical intermediate for constructing complex molecular architectures with high stereochemical control. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs), novel agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring cyclopropane rings for conformational restriction and metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the cyclopropyl group can enhance biological activity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals requiring specific chiral centers.
• Academic & Industrial Research: A valuable reagent in method development for new cyclopropanation, condensation, and asymmetric synthesis reactions.
• Material Science: Potential monomer or cross-linking agent in the development of polymers with tailored thermal and mechanical properties.

Basic Information

Product Name	4-Cyclopropyl-3-Oxo-Butyric Acid Ethyl Ester
CAS No.	630399-84-7
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	Ethyl 4-cyclopropyl-3-oxobutanoate; 3-Oxobutanoic acid, 4-cyclopropyl-, ethyl ester; Ethyl 4-cyclopropylacetoacetate; 4-Cyclopropylacetoacetic acid ethyl ester; Ethyl (4-cyclopropyl-3-oxo)butyrate; Butyric acid, 4-cyclopropyl-3-oxo-, ethyl ester; 4-Cyclopropyl-3-oxobutyric acid ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Cyclopropyl-3-Oxo-Butyric Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.