Description

4-Ethynylpyridine is a versatile heterocyclic building block featuring both a pyridine ring and a terminal alkyne functional group. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and materials science industries for applications in ligand synthesis, polymer chemistry, and the creation of novel molecular frameworks.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor research.
• Ligand Synthesis: Used to create sophisticated ligands for catalysis and metal-organic frameworks (MOFs) due to its coordinating pyridine nitrogen and modifiable alkyne group.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for developing specialty polymers, conductive materials, and functional surfaces via click chemistry.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Bioconjugation: Enables site-specific labeling of biomolecules (proteins, nucleic acids) through copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Organic Electronic Materials: Precursor for constructing π-conjugated systems used in organic light-emitting diodes (OLEDs) and semiconductors.

Basic Information

Product Name	4-Ethynylpyridine
CAS No.	630127-51-4
Molecular Formula	C7H5N
Molecular Weight	103.12 g/mol
Synonyms	4-Pyridylethyne; 4-(Ethynyl)pyridine; Pyridine, 4-ethynyl-; 4-Ethynyl-pyridine; 4-Pyridinylacetylene
EINECS	Contact for details

Quality Control

Our 4-Ethynylpyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For customers with specific regulatory needs, we can discuss compliance with relevant standards on request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.