Description

4-(4-Amino-3-Fluoro-Phenoxy)-Pyridine-2-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both an amino-fluorophenoxy moiety and a pyridine-carbonitrile group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its fluorine and nitrogen-containing heterocycle.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes due to its modifiable functional groups.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated aromatic ethers.

Basic Information

Product Name	4-(4-Amino-3-Fluoro-Phenoxy)-Pyridine-2-Carbonitrile
CAS No.	630125-69-8
Molecular Formula	C₁₂H₈FN₃O
Molecular Weight	229.21 g/mol
Synonyms	4-(4-Amino-3-fluorophenoxy)picolinonitrile; 2-Pyridinecarbonitrile, 4-[(4-amino-3-fluorophenyl)oxy]-; 4-[(4-Amino-3-fluorophenyl)oxy]-2-pyridinecarbonitrile; 4-(4-Amino-3-fluoro-phenoxy)-pyridine-2-carbonitrile; 630125-69-8; 4-(4-Amino-3-fluorophenoxy)-2-cyanopyridine; 4-(4-Amino-3-fluoro-phenoxy)-2-cyano-pyridine
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Amino-3-Fluoro-Phenoxy)-Pyridine-2-Carbonitrile is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.