Description

2-(Piperidin-4-Yl)Nicotinonitrile is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a piperidine and a cyanopyridine moiety, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, kinase inhibition, and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways and protein function.
• Material Science Research: Investigated as a building block for advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or functional polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for client projects.

Basic Information

Product Name	2-(Piperidin-4-Yl)Nicotinonitrile
CAS No.	630116-81-3
Molecular Formula	C11H11N3
Molecular Weight	185.23 g/mol
Synonyms	2-(4-Piperidinyl)nicotinonitrile; 2-(Piperidin-4-yl)nicotinonitrile; 3-Cyano-2-(4-piperidinyl)pyridine; Nicotinonitrile, 2-(4-piperidinyl)-; 2-(Piperidin-4-yl)pyridine-3-carbonitrile; 4-(3-Cyanopyridin-2-yl)piperidine
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-4-Yl)Nicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.