Description

5-[(Aminooxy)Methyl]-2-(1H-Pyrazol-1-Yl)Pyridine is a specialized heterocyclic building block featuring both an aminooxy and a pyrazole functional group. This unique bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry and agrochemical discovery. The compound's reactivity profile enables its use in conjugation and linker chemistry for creating novel bioactive entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Bioconjugation & Linker Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted therapies due to its reactive aminooxy group.
• Agrochemical Research: Serves as a precursor in the design and synthesis of new pesticides and herbicides with enhanced activity.
• Chemical Biology Probes: Used to create molecular probes for studying enzyme function and protein interactions.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Academic & Contract Research: Essential reagent for universities and CROs conducting cutting-edge synthetic chemistry projects.

Basic Information

Product Name	5-[(Aminooxy)Methyl]-2-(1H-Pyrazol-1-Yl)Pyridine
CAS No.	628703-61-7
Molecular Formula	C9H10N4O
Molecular Weight	190.20 g/mol
Synonyms	2-(1H-Pyrazol-1-yl)-5-[(aminooxy)methyl]pyridine; 5-(Aminooxymethyl)-2-(1H-pyrazol-1-yl)pyridine; 2-Pyrazol-1-yl-5-aminoxymethylpyridine; 1-(5-((Aminooxy)methyl)pyridin-2-yl)-1H-pyrazole; (Pyridin-2-yl-pyrazol-1-yl-methyl)-hydroxylamine; 628703-61-7; 5-(Aminomethyloxy)-2-(pyrazol-1-yl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-[(Aminooxy)Methyl]-2-(1H-Pyrazol-1-Yl)Pyridine is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is available upon request. We support cGMP-compliant production for advanced development phases.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.