Description

2-Chloro-3-Fluoro-4-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring chlorine, fluorine, and a trifluoromethyl group on the pyridine ring, makes it an essential intermediate for creating compounds with tailored electronic and steric properties. This specialty chemical is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for synthesizing functionalized ligands, organic electronic materials, and liquid crystals.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical manufacturers for the production of custom-designed molecules for client-specific applications.

Basic Information

Product Name	2-Chloro-3-Fluoro-4-(Trifluoromethyl)Pyridine
CAS No.	628692-22-8
Molecular Formula	C7H2ClF4N
Molecular Weight	199.54 g/mol
Synonyms	2-Chloro-3-fluoro-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-2-chloro-3-fluoropyridine; Pyridine, 2-chloro-3-fluoro-4-(trifluoromethyl)-; 2-Chloro-3-fluoro-4-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated pyridine intermediates. Every batch is analyzed using advanced techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality system is designed to support cGMP and ISO standards for traceability and reliability, essential for regulated R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.