Description

Methyl 2-Chloro-3-Fluoro-4-Pyridinecarboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated pyridine core enables precise molecular modifications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Research: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and developing novel chemical entities.
• Fine Chemical Production: Acts as a building block for manufacturing complex fine chemicals and other specialty intermediates.

Basic Information

Product Name	Methyl 2-Chloro-3-Fluoro-4-Pyridinecarboxylate
CAS No.	628691-95-2
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	2-Chloro-3-fluoro-4-pyridinecarboxylic acid methyl ester; Methyl 2-chloro-3-fluoropyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 2-chloro-3-fluoro-, methyl ester; 2-Chloro-3-fluoropyridine-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-3-Fluoro-4-Pyridinecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.