Description

2-Chloro-3-Fluoropyridine-4-Carboxylic Acid is a high-value, multifunctional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated pyridine core structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals and organic semiconductors, due to its electron-withdrawing characteristics.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-3-Fluoropyridine-4-Carboxylic Acid
CAS No.	628691-93-0
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.54 g/mol
Synonyms	4-Pyridinecarboxylic acid, 2-chloro-3-fluoro-; 2-Chloro-3-fluoroisonicotinic acid; 3-Fluoro-2-chloropyridine-4-carboxylic acid; 2-Chloro-3-fluoropyridine-4-carboxylic acid; 2-Chloro-3-fluoro-4-pyridinecarboxylic acid; 2-Chloro-3-fluoro-4-carboxypyridine; 4-Carboxy-2-chloro-3-fluoropyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluoropyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports your regulatory needs for research and commercial development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.