Description

1H-Isoindole-1,3(2H)-Dione,2-[[6-(Chloromethyl)-2-Pyridinyl]Methyl]- is a specialized heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its molecular architecture, featuring both phthalimide and chloromethylpyridine moieties, makes it a versatile intermediate for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection products, leveraging its reactive chloromethyl group.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional coatings.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein interactions.
• Ligand Synthesis: Acts as a starting material for creating novel chelating ligands used in catalysis and metal recovery processes.
• Academic & Industrial R&D: Fundamental building block in exploratory organic chemistry for constructing novel heterocyclic frameworks.

Basic Information

Product Name	1H-Isoindole-1,3(2H)-Dione,2-[[6-(Chloromethyl)-2-Pyridinyl]Methyl]-
CAS No.	628308-52-1
Molecular Formula	C₁₅H₁₁ClN₂O₂
Molecular Weight	286.71 g/mol
Synonyms	2-((6-(Chloromethyl)pyridin-2-yl)methyl)isoindoline-1,3-dione; N-(6-(Chloromethyl)pyridin-2-yl)methyl)phthalimide; Phthalimide, 2-[[6-(chloromethyl)-2-pyridinyl]methyl]-; 2-((6-(Chloromethyl)-2-pyridyl)methyl)phthalimide; 2-[[6-(Chloromethyl)-2-pyridinyl]methyl]-1H-isoindole-1,3(2H)-dione; CAS 628308-52-1
EINECS	Contact for details

Quality Control

Our production of 1H-Isoindole-1,3(2H)-Dione,2-[[6-(Chloromethyl)-2-Pyridinyl]Methyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.