Description

3-Chloro-2-Hydroxy-5-Formylpyridine is a versatile heterocyclic building block characterized by its distinct functional groups, including a formyl group, a hydroxyl group, and a chloro substituent. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for use as a key intermediate.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of functionalized polymers, coordination polymers, and organic electronic materials due to its reactive aldehyde group.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and fluorescent markers for biochemical and diagnostic applications.

Basic Information

Product Name	3-Chloro-2-Hydroxy-5-Formylpyridine
CAS No.	627501-18-2
Molecular Formula	C6H4ClNO2
Molecular Weight	157.55 g/mol
Synonyms	5-Formyl-3-chloro-2-hydroxypyridine; 3-Chloro-2-pyridinol-5-carboxaldehyde; 3-Chloro-2-oxo-1,2-dihydropyridine-5-carbaldehyde; 3-Chloro-5-formyl-2(1H)-pyridinone; 3-Chloro-2-hydroxypyridine-5-carbaldehyde; 3-Chloro-5-pyridinecarboxaldehyde, 2-hydroxy-; 2-Hydroxy-3-chloro-5-formylpyridine
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Hydroxy-5-Formylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.