Description

Methyl 2-(4-Bromo-3-Nitrophenyl)Acetate is a high-purity, versatile aromatic ester building block critical for advanced organic synthesis. Its molecular structure, featuring both bromo and nitro substituents, makes it an essential intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), functional materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides and fungicides, leveraging the reactivity of its halogen and nitro functional groups.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and photoactive polymers due to its electron-withdrawing substituents.
• Cross-Coupling Reactions: The bromoaryl group makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Functional Dye & Pigment Intermediate: Employed in the synthesis of specialized azo dyes and pigments where nitro and ester groups contribute to color and stability properties.
• Academic & Contract Research: A valuable reagent for university laboratories and CROs (Contract Research Organizations) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Methyl 2-(4-Bromo-3-Nitrophenyl)Acetate
CAS No.	627490-22-6
Molecular Formula	C9H8BrNO4
Molecular Weight	274.07 g/mol
Synonyms	Methyl (4-Bromo-3-nitrophenyl)acetate; Acetic acid, 2-(4-bromo-3-nitrophenyl)-, methyl ester; 4-Bromo-3-nitrophenylacetic acid methyl ester; Methyl 4-bromo-3-nitrophenylacetate; 2-(4-Bromo-3-nitrophenyl)acetic acid methyl ester; Methyl α-(4-bromo-3-nitrophenyl)acetate; Methyl (4-bromo-3-nitrobenzyl)acetate (common name variant)
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-(4-Bromo-3-Nitrophenyl)Acetate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.